Sceletium tortuosum, calmness and clarity.
A standardised 5% total alkaloid Sceletium powder extract with a high mesembrine profile, supplied in bulk to brands, formulators and manufacturers worldwide.
Sceletium tortuosum
5% total alkaloids
Standardised to 4.5-5.5% (45-55 mg/g)
Two alkaloid profiles
Mesembrine forward and Balanced
Two extraction types
Water based or solvent based
CoA per batch
Six alkaloids measured
Legal to export
Non-scheduled botanical
Fluxion Biotech is a South African biotech manufacturer specialising in botanical extraction. We source Sceletium plant material and extract its alkaloids to produce a standardised 5% total alkaloid Kanna extract powder with a high mesembrine profile.
We partner with brands to develop and produce natural wellness solutions built on scientific credibility and clean label formulation, supported by traceable sourcing and export ready documentation.
Whether you need samples for product development or bulk Kanna powder for production runs, we supply Sceletium extract wholesale to brands in South Africa and abroad.
Sceletium plant material from growers with Traditional Knowledge Benefit-Sharing Agreements
Alkaloids extracted from the plant material and standardised to 45-55 mg/g total alkaloids
Bulk powder supplied with a Certificate of Analysis per batch and export ready documentation
Two extraction types and two alkaloid profiles, all standardised to 45-55 mg/g (4.5-5.5%) total alkaloids.
Clean green product.
Water and solvent based extractions.
Both alkaloid profiles are available with either extraction type.
| Alkaloid | Concentration |
|---|---|
| Mesembrine | 25-50 mg/g |
| Mesembrenone | 1-20 mg/g |
| Δ7-Mesembrenone | 1-10 mg/g |
| Total alkaloids | 45-55 mg/g (4.5-5.5%) |
Standardised powder. A high mesembrine Kanna extract for precise formulation.
| Alkaloid | Concentration |
|---|---|
| Mesembrine | 5-20 mg/g |
| Mesembrenone | 5-30 mg/g |
| Mesembrine alcohols (mesembrenol, mesembranol, epimesembranol) | 5-20 mg/g |
| Total alkaloids | 45-55 mg/g (4.5-5.5%) |
Standardised powder. A broader alkaloid spread across mesembrine, mesembrenone and the mesembrine alcohols.
The Sceletium extract range is a versatile ingredient platform for gummies, chocolate, nasal sprays, honey, capsules, tablets and functional beverages. Brands, formulators and manufacturers can select the potency, delivery format and dosage profile best suited to their product concept, target consumer and regulatory environment.
Gummies have become the format of choice for consumers who want their wellness ritual to feel like a pleasure, not a chore. The Sceletium gummy concept brings together a botanically rich extract, a vibrant flavour palette and a format that travels well, photographs beautifully and sits naturally in the modern lifestyle supplement aisle.
Discuss this formatGummies, application 1 of 6
In South Africa, Sceletium biomass is protected and regulated by the Department of Forestry, Fisheries and the Environment (DFFE) under the National Environmental Management: Biodiversity Act (NEMBA, Act 10 of 2004) and the Bioprospecting, Access and Benefit-Sharing (BABS) regulations.
Biomass is sourced from growers that hold Traditional Knowledge Benefit-Sharing Agreements (or are currently in negotiations) with the South African San Council and the National Khoi-San Council.
Sceletium is a legal, non-scheduled botanical. It is not classified as a controlled drug, and its raw material and extracts can be exported under standard export procedures. A Certificate of Analysis (CoA) is provided with each batch together with any additional testing required for export compliance.
Fluxion Biotech is a member of the Southern African Botanical Products Association.
Fluxion Biotech uses MS Analytical Services for its alkaloid analysis.
A partnership with Varsfontein, a fifth-generation Karoo family farm, sharing expertise in Sceletium tortuosum and botanicals.
Sceletium tortuosum, also known as Kanna or Kougoed, is a succulent plant used for centuries by the San and Khoikhoi people of Southern Africa for its mood enhancing, stress relieving and cognitive support properties.
The Afrikaans name Kougoed means "something to chew", after the traditional practice of crushing, fermenting and drying the plant before use. Modern science has studied these traditional uses through clinical and preclinical research, turning a heritage plant into a recognised ingredient in the global mental wellness market.
Sceletium's active compounds work through mechanisms associated with serotonin reuptake inhibition and PDE4 inhibition, pathways linked to natural mood regulation, offering a gentle, non-stimulant route to improved mood, reduced stress and greater mental clarity.
Interest in Sceletium is growing as consumers seek botanicals with traceable origins, scientific credibility and a compelling brand story.
The mesembrine extract profile brings together complementary mechanisms.
A monoamine releasing agent and potent Serotonin Reuptake Inhibitor that maintains elevated serotonin levels in synaptic pathways, supporting mood uplift and reducing situational anxiety.
Strong PDE4 inhibitory activity, slowing cAMP degradation to support neuronal signalling, emotional steadiness and cognitive clarity without autonomic overstimulation.
Anti-inflammatory and tyrosinase enzyme inhibition properties.
Have a specific formulation in mind?
Let's talk about your productTell us the alkaloid profile and volume you need.
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